Description / Application
Nicorandil is a pyrimidinecarboxamide that is nicotinamide in which one of the hydrogens attached to the carboxamide nitrogen is replaced by a 2-(nitrooxy)ethyl group. It has both nitrate-like and ATP-sensitive potassium channel activator properties, and is used for the prevention and treatment of angina pectoris. It has a role as a vasodilator agent and a potassium channel opener. It is a pyridinecarboxamide and a nitrate ester. It is functionally related to a nicotinamide.
Identities
| Alternative Name | Ikorel, 2-(Pyridine-3-carbonylamino)ethyl nitrate |
|---|---|
| Molecular Formula | C8H9N3O4 |
| Molecular Weight | 211.17 |
| MFCD | MFCD00186520 |
Safety
| Pictograms |
|
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302;H318 |
| Precautionary Statements | P264;P270;P280;P301+P312;P305+P351+P338;P310;P330;P501 |