Description / Application
Vorinostat is a dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL). It has a role as an antineoplastic agent, an EC 3.5.1.98 (histone deacetylase) inhibitor and an apoptosis inducer. It is a hydroxamic acid and a dicarboxylic acid diamide. It is functionally related to a hydroxylamine, an aniline and a suberic acid.
Identities
| Alternative Name | N-Hydroxy-N'-phenyl-octanediamide; Suberoylanilide hydroxamic acid; SAHA |
|---|---|
| Molecular Formula | C14H20N2O3 |
| Molecular Weight | 264.32 |
| MFCD | MFCD00945317 |
Safety
| Pictograms |
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|---|---|
| Signal Word | Danger |
| Hazard Statements | H341;H360 |
| Precautionary Statements | P201;P202;P281;P308+P313;P405;P501 |