Description / Application
YK-4-279 is a member of the class of indolones that is 1,3-dihydro-2H-indol-2-one substituted by hydroxy, 2-(4-methoxyphenyl)-2-oxoethyl, chloro, and chloro groups at positions 3, 3, 4, and 7, respectively. It blocks RNA helicase A binding to EWS-FLI1, induces apoptosis, and exhibits antineoplastic activity. It has a role as an antineoplastic agent and an apoptosis inducer. It is a member of indolones, a monomethoxybenzene, a tertiary alcohol, an organochlorine compound and an aromatic ketone.
Identities
| Alternative Name | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one |
|---|---|
| Molecular Formula | C17H13Cl2NO4 |
| Molecular Weight | 366.2 |
| MFCD | MFCD18382120 |
Safety
| Pictograms |
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|---|---|
| Signal Word | Warning |
| Hazard Statements | H315;H319;H335 |
| Precautionary Statements | P261;P264;P271;P280;P302+P352;P304+P340;P305+P351+P338;P312;P321;P332+P313;P337+P313;P362;P403+P233;P405;P501 |