Description / Application
Bortezomib is L-Phenylalaninamide substituted at the amide nitrogen by a 1-(dihydroxyboranyl)-3-methylbutyl group and at Nalpha by a pyrazin-2-ylcarbonyl group. It is a dipeptidyl boronic acid that reversibly inhibits the 26S proteasome. It has a role as an antineoplastic agent, an antiprotozoal drug, a protease inhibitor and a proteasome inhibitor. It is an amino acid amide, a member of pyrazines and a L-phenylalanine derivative. It is functionally related to a boronic acid.
Identities
| Alternative Name | MG-341; PS-341 |
|---|---|
| Molecular Formula | C19H25BN4O4 |
| Molecular Weight | 384.2 |
| MFCD | MFCD09056737 |
Transport
| DOT UN Number | UN3249 |
|---|---|
| Hazard Class | 6.1 |
| Packing Group | II |
Safety
| Pictograms |
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|---|---|
| Signal Word | Warning |
| Hazard Statements | H300;H310;H330;H372 |
| Precautionary Statements | P260;P284;P301+P310;P304+P340;P320;P330;P361;P302+P350;P405;P501 |