Description / Application
Abacavir is a 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection. It has a role as an antiviral drug, a HIV-1 reverse transcriptase inhibitor and a drug allergen.
Identities
| Alternative Name | Ziagen |
|---|---|
| Molecular Formula | C14H18N6O |
| Molecular Weight | 286.33 |
| MFCD | MFCD00903850 |
Safety
| Pictograms |
|
|---|---|
| Signal Word | Danger |
| Hazard Statements | H351;H361;H317;H334;H341 |
| Precautionary Statements | P501;P261;P202;P285;P201;P280;P272;P308+P313;P304+P341;P302+P352;P333+P313;P363;P405 |