HTH-01-015

HTH-01-015 is an organic heterotetracyclic compound that is 5,13-dihydro-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one substituted by methyl groups at positions 4, 5 and 13, and by a [1-(piperidin-4-yl)-1H-pyrazol-4-yl]amino group at position 2. It is a potent NUAK1 inhibitor (IC50 = 100 nM). It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a member of piperidines, a member of pyrazoles, an aromatic amine, an organic heterotetracyclic compound, a secondary amino compound and a tertiary amino compound.