Description / Application
Zuranolone is a 3-hydroxy steroid that is 5beta-19-norpregnane substituted by hydroxy, methyl, oxo, and 4-cyano-1H-pyrazol-1-yl groups at positions 3, 3, 20 and 21, respectively. It is a positive allosteric modulator of GABAA receptor developed by Sage Therapeutics and Biogen for the treatment of postpartum depression in adults. It has a role as an antidepressant, an anticonvulsant and a GABA modulator. It is a nitrile, a member of pyrazoles, a 3-hydroxy steroid and a 20-oxo steroid.
Identities
| Alternative Name | SAGE-217 |
|---|---|
| Molecular Formula | C25H35N3O2 |
| Molecular Weight | 409.6 |
| MFCD | MFCD31619241 |
Safety
| Pictograms |
|
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315;H319;H335 |
| Precautionary Statements | P261;P264;P271;P280;P302+P352;P304+P340;P305+P351+P338;P312;P321;P332+P313;P337+P313;P362;P403+P233;P405;P501 |